We are hiring! Two PhD studentships are currently available in the labs of Susanne Schoch, Dirk Dietrich and our own. The aim is to develop new optical sensors for the NMDA receptor co-agonists D-serine and glycine and to visualize their signaling with already established and newly designed sensors. We will then dissect to what extent and by what mechanisms neurons and astrocytes provide NMDA receptors with either co-agonist in the rodent hippocampus and how they thereby shape synaptic plasticity. Please see here for the full text of the job advertisement.
Please have a look at one of our recent papers to get an idea of what the project is roughly about:
Zhang WH, Herde MK, Mitchell JA, Whitfield JH, Wulff AB, Vongsouthi V, Sanchez-Romero I, Gulakova PE, Minge D, Breithausen B, Schoch S, Janovjak H, Jackson CJ, Henneberger C (2018) Monitoring hippocampal glycine with the computationally designed optical sensor GlyFS. Nat. Chem. Biol. (link).